Medical & Dental

Ulf Landegren

Proximity ligation protein-detection assay

SwedenEvidence: high confidenceChecked July 2026

Ulf Landegren co-invented proximity ligation assays, diagnostic molecular tools that detect proteins through paired binding probes and DNA amplification. Uppsala University identifies proximity assays as central methods from his group with broad use in clinical medicine, and a 2025 cancer-research award records his active work on protein analysis.

01

What Ulf did

Co-invented proximity ligation assays that turn paired protein-recognition events into amplifiable DNA signals.

02

Why it matters

Proximity ligation made highly sensitive, multiplexable protein detection practical in solution and tissue samples.

03

Living-status check

Uppsala's current research profile lists Landegren as research leader and 2025 work, while Cancerfonden lists his 2025 cancer-analysis project.