Medical & Dental

David Klenerman

Sequencing-by-synthesis DNA instrument

United KingdomEvidence: high confidenceChecked July 2026

David Klenerman co-invented sequencing-by-synthesis, the physical DNA-reading approach commercialized in high-throughput sequencing instruments. By making parallel DNA analysis practical at scale, the technology changed how laboratories build genomic data for medicine, biological research and public-health surveillance.

01

What David did

Co-invented sequencing-by-synthesis with Shankar Balasubramanian.

02

Why it matters

NIHF identifies sequencing-by-synthesis as a next-generation sequencing method that made high-throughput DNA analysis practical.

03

Living-status check

NIHF records Klenerman's 2024 induction, a positive dated public award event confirming he was alive in 2024.